Naltrexone is an opiate antagonist predominantly used to treat alcohol dependence. It is also often used, along with other methods, to reduce opioid use, and less frequently in a wide range of off-label uses which may or may not be related to addiction.

The medication is more commonly known by the brand names Revia or Depade, both of which come as tablets. In some areas it is possible buy naltrexone as Vivitrol, which is administered via injection.

Naltrexone for Alcohol Dependency

Naltrexone is most commonly used to treat alcohol addiction, and is arguably most effective when used for this purpose. It has two important functions:

• Reduces the cravings for alcohol; and
• Reduces the pleasure derived from drinking.

The majority of people buy naltrexone as part of a larger program to curtail drinking, including support groups, lifestyle changes, and possibly other medications. Such a scenario is desirable if available--there is a great deal of evidence that shows breaking an addiction is more likely to be successful with these extra measures--but naltrexone has also proven to be effective without them.

In fact, there is some evidence that, for at least some individuals, the medication is actually more effective if taken while drinking continues. The reduction in pleasure from drinking naturally reduces cravings--since there is no longer any reward--and eventually the habit is broken through loss of interest. This method tends to minimize the psychological withdrawal and willpower battles encountered with going cold turkey.

In both cases one 50 mg tablet is taken once per day. Treatment typically continues for 12 weeks.

Naltrexone for Opioid Addiction

Similar to use in alcohol addiction, naltrexone diminishes the pleasant effects of opioids such as heroin, opium, methadone, codeine and so forth. An important distinction, however, is that it does not diminish cravings; for this reason the medication is not as successful as when it is used for overcoming alcohol addiction.

Patients planning to buy naltrexone to beat opioid addiction should at the minimum have desire and determination to quit, and other support is strongly recommended. Without determination and support, the temptation to skip a dose of naltrexone and restore the effects of opioids may be extraordinarily difficult to overcome.

Naltrexone therapy should be started after the patient has been opioid-free for at least 7 days; otherwise the medication could trigger severe physical withdrawal symptoms. A half-dose of 25 mg should be taken the first time to ensure no withdrawal symptoms do develop. Assuming the first dose goes well, 50 mg per day is taken for three to six months, though treatment may be extended if needed.

Off-Label Uses

Naltrexone is increasingly used for various off-label purposes, with varying degrees of success, including:

• Fibromyalgia
• Multiple sclerosis
• Certain Cancers
• Certain autistic behaviors
• Depersonalization disorder
• Impulse control disorders
• Smoking cessation

There is relatively little documentation regarding the effectiveness of the treatment in off-label uses, so there are no widely-accepted dosage & administration guidelines and it might be difficult to get a prescription to buy naltrexone for such conditions.

On the plus side, off-label uses typically involve low doses (under 50 mg per day) and are very unlikely to cause significant side effects. Keep in mind, however, that the medication will reduce the effectiveness of opioid painkillers.

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